IGF-1 LR3

Dragon Pharma
  • Active Substance: Insulin-like Growth Factor 1, Long R3 (IGF-1 LR3)
  • Concentration: 1 mg per vial
  • Pack Size: Lyophilized injectable vial
  • Manufacturer: Dragon Pharma
  • Brand Name: IGF-1 LR3
  • Molecular Formula: C400H625N111O115S6
  • Molecular Weight: ~9111 Da
  • Synonyms: Long R3 IGF-1, LR3 IGF-1, IGF1 analogue
$90.00
$90.00
In Stock
Manufacturer Dragon Pharma
Brand IGF-1 LR3
Substance Insulin-like Growth Factor 1
Concentration 1 mg
Pack Size vial
Shipping

IGF-1 LR3 1 mg by Dragon Pharma is a potent research peptide derived from the Insulin-like Growth Factor 1 protein with an extended half-life due to amino acid modification. Known for its anabolic and regenerative effects, IGF-1 LR3 is used in studies focused on cell proliferation, satellite cell activation, and tissue recovery in muscle degeneration models.

Mechanism of Action

IGF-1 LR3 functions by binding to IGF-1 receptors and insulin receptors in skeletal muscle, activating the PI3K/Akt and MAPK/ERK pathways. This interaction promotes anabolic signaling, protein synthesis, and myogenic differentiation. The LR3 variant (Long Arg3) prevents IGF binding protein interference and extends bioavailability to over 20–30 hours.

Because it resists degradation and binds less to serum proteins, IGF-1 LR3 is more efficient than standard IGF-1 in stimulating satellite cell recruitment and muscle fiber regeneration. It is also investigated for anti-aging effects due to its influence on cell longevity, mitochondrial health, and tissue healing capacity.

Key Features & Benefits

  • Extended Half-Life: Modified structure allows 20–30 hours of biological activity vs. ~30 minutes for native IGF-1.
  • Supports Muscle Research: Promotes hyperplasia, hypertrophy, and stem cell activation in damaged muscle models.
  • Cellular Rejuvenation: Studied for anti-aging and regenerative properties on a systemic level.
  • Anabolic Signaling: Triggers powerful protein synthesis via IGF-1 and insulin receptor pathways.
  • High Purity Peptide: Dragon Pharma's IGF-1 LR3 is produced to research-grade standards with strict quality control.

Frequently Asked Questions

1. What is IGF-1 LR3 used for in research?
It is studied for muscle regeneration, tissue healing, and cellular repair in both sports science and aging models.
2. How is IGF-1 LR3 different from regular IGF-1?
IGF-1 LR3 has a longer half-life and reduced binding to IGFBPs, making it more bioactive in circulation.
3. Is IGF-1 LR3 anabolic?
Yes, it promotes both muscle hypertrophy and hyperplasia by activating protein synthesis and satellite cells.
4. What's the proper storage for IGF-1 LR3?
Store the lyophilized vial at -20°C and refrigerate at 2–8°C after reconstitution.