Decapeptide-12
- Product Title: Decapeptide-12
- Active Substance: Decapeptide-12
- Concentration: 200 mg
- Pack Size: Topical
- Manufacturer: Peptide Sciences USA
- Brand Name: Decapeptide
- Molecular Formula: C65H90N18O17
- Molecular Weight: 1311.46 g/mol
- Sequence: Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr
- Synonyms: YRSRKYSSWY, Lumixyl
Decapeptide-12 200 mg – Lighthouse of Radiant Skin
Product Summary
Picture a research horizon where skin glows uniformly, dark spots fade, and aging slows. Decapeptide-12 200 mg from Peptide Sciences USA, a potent tyrosinase inhibitor, makes this vision a reality. By reducing melanin production, Decapeptide-12 addresses hyperpigmentation, enhances skin tone, and supports anti-aging, offering a prestigious tool for transformative skin health research.
How Decapeptide-12 Works
Decapeptide-12, a synthetic oligopeptide with the sequence Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr, is a highly effective tyrosinase inhibitor. It binds reversibly to tyrosinase, the copper-containing enzyme responsible for melanin synthesis, blocking phenol oxidation and reducing melanin production by 27–43% in cultured melanocytes over 7 days. This mechanism targets hyperpigmentation conditions like melasma and solar lentigines without the cytotoxicity associated with hydroquinone, offering up to 17 times greater potency.
In preclinical studies, topical Decapeptide-12 (0.01%) reduced melasma by 40–50% after 12–16 weeks and achieved complete clearance in 25% of subjects with Fitzpatrick type IV skin. It also upregulates sirtuin genes (SIRT1 by 141%, SIRT3 by 121%, SIRT6 by 147%), enhancing cellular resistance to oxidative stress and supporting DNA repair, which contributes to anti-aging effects. These properties make it ideal for researching skin lightening, anti-aging, and even food preservation.
Why Choose Decapeptide-12 200 mg?
Decapeptide-12 is a vanguard in skin health and anti-aging research, offering transformative benefits. Here's why it excels:
- Hyperpigmentation Reduction: Inhibits tyrosinase, reducing melanin by 27–43% and clearing melasma in up to 40% of subjects, ideal for skin lightening studies.,
- Anti-Aging Support: Upregulates SIRT1, SIRT3, and SIRT6, enhancing DNA repair and cellular resistance to oxidative stress for youthful skin.,
- Safe Alternative: 17x more potent than hydroquinone without cytotoxicity, minimizing irritation in sensitive skin models.
- Broad Applications: Supports research into melasma, solar lentigines, post-inflammatory hyperpigmentation, and non-cosmetic uses like food preservation.
- Premier Quality: Peptide Sciences USA ensures 99% purity through advanced synthesis, guaranteeing reliable research outcomes.
Decapeptide-12 200 mg empowers researchers to brighten skin health research, backed by cutting-edge peptide science.
Product Specifications
Peptide Sciences USA's Decapeptide-12 200 mg is crafted for precision in skin health research, delivering exceptional quality. Here's the breakdown:
- Composition: Contains 200 mg of Decapeptide-12 (C65H90N18O17, molecular weight 1311.46 g/mol).
- Pack Size: Topical
- Manufacturing: Produced by Peptide Sciences USA with 99% purity, verified by High-Performance Liquid Chromatography and Mass Spectrometry.
- Usage Guidelines: Reconstitute with a solvent (e.g., sterile water, DMSO) and apply topically at 0.01–0.05% concentration, often with microneedles or chemical enhancers to improve skin penetration, in research protocols under professional supervision.
- Storage: Store lyophilized powder at -20°C. After reconstitution, refrigerate at 2–8°C and use within 30 days to maintain potency.,
- Safety: Preclinical studies report minimal side effects like mild skin irritation, erythema, or dryness; limited human data requires research oversight.
This peptide is for research purposes only, providing a robust platform for studying skin lightening and anti-aging.
Legal Disclaimer
Decapeptide-12 200 mg is supplied for research purposes only and is not FDA-approved for human use. It is not intended to diagnose, treat, cure, or prevent any condition. Consult a licensed professional before use. Peptide Sciences USA assumes no liability for misuse. All information is educational and based on preclinical research.
Frequently Asked Questions
What is the use of Decapeptide-12?
Pillows of Decapeptide-12 are used in research to explore skin lightening and hyperpigmentation treatment by inhibiting tyrosinase, reducing melanin production. It's studied for melasma, solar lentigines, post-inflammatory hyperpigmentation, and potential non-cosmetic applications like food preservation.,
What are the benefits of Decapeptide-12?
Decapeptide-12 reduces melanin production by 27–43%, clears melasma in up to 40% of subjects, and enhances skin tone and elasticity. It upregulates sirtuin genes (SIRT1, SIRT3, SIRT6) for anti-aging, offering a safer, more potent alternative to hydroquinone.,
What are the side effects of Decapeptide-12?
Preclinical studies report minimal side effects, such as mild skin irritation, slight erythema, or dryness in sensitive skin models. Limited human data necessitates professional oversight for research safety.,
How is Decapeptide-12 200 mg applied in research?
Decapeptide-12 is supplied as a 200 mg lyophilized powder. Reconstitute with a solvent (e.g., sterile water, DMSO) and apply topically at 0.01–0.05% concentration, often with microneedles or chemical enhancers, in research protocols under professional guidance.,
How should Decapeptide-12 200 mg be stored?
Store the lyophilized powder at -20°C. After reconstitution with a solvent, refrigerate at 2–8°C and use within 30 days to maintain potency.,
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