Humanin 10 mg
- Active Substance: Humanin
- Concentration: 10 mg per vial
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Humanin
- Molecular Formula: C119H204N34O32S
- Molecular Weight: ~2687 g/mol
- Sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
- Synonyms: Mitochondrial-Derived Peptide, HN
Humanin 10 mg – Beacon of Cellular Vitality
Ignite a Neuroprotective Revolution
Envision a research frontier where neurons thrive, mitochondria flourish, and aging slows. Humanin 10 mg from Peptide Sciences USA lights this fire. This mitochondrial-derived peptide shields cells from apoptosis, protects against Alzheimer's-related insults, and boosts vitality, fueling breakthroughs in neuroprotection and anti-aging. It's your beacon for unlocking transformative discoveries, crafted for visionary researchers like you.
The Science That Ignites Vitality
Humanin (sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala) is a 24-amino acid mitochondrial-derived peptide (MDP) encoded by the MT-RNR2 gene in the 16S rRNA region of mtDNA. It binds to the tripartite receptor complex (gp130/WSX1/CNTFR) and formyl peptide receptor 2, activating AKT/ERK1/2 and STAT3 pathways to inhibit apoptosis and reduce oxidative stress. In preclinical models, Humanin suppresses neuronal death induced by amyloid-beta (Aβ) and familial Alzheimer's disease (FAD) genes (e.g., mutant APP, PS1, PS2), reducing Aβ plaque accumulation by up to 50% in transgenic mice.
Humanin enhances mitochondrial function, improves insulin sensitivity, and reduces inflammation, making it ideal for researching Alzheimer's, cardiovascular health, and diabetes. Its analog HNG (S14G-Humanin) enhances spatial learning and memory in AD mouse models, while Humanin's cytoprotective effects extend to heart, retina, and muscle tissues. The 10 mg dosage offers precision for high-impact studies in neuroprotection, mitochondrial health, and longevity.
Why Humanin 10 mg is Your Research Trailblazer
Humanin isn't just a peptide—it's a spark that redefines neuroprotective research. Here's why it shines:
- Neuroprotection Surge: Shields neurons from Aβ and FAD gene toxicity, reducing Alzheimer's pathology in preclinical models.
- Mitochondrial Booster: Enhances mtDNA function and reduces oxidative stress, ideal for aging and metabolic studies.
- Anti-Apoptotic Power: Inhibits cell death via Bax and IGFBP-3 interactions, supporting multi-organ research.
- Anti-Aging Edge: Increases lifespan in C. elegans and supports vitality in mammals, driving longevity research.
- Elite Quality: Crafted by Peptide Sciences USA with 99% purity, ensuring your research dazzles with precision.
With Humanin 10 mg, you're not just researching—you're igniting a revolution in neuroprotective and anti-aging science.
Product Specifications
Peptide Sciences USA's Humanin 10 mg is your catalyst for groundbreaking neuroprotective research. Here's the breakdown:
- Composition: Contains 10 mg Humanin (C119H204N34O32S, ~2687 g/mol).
- Pack Size: Single vial of lyophilized powder, requiring reconstitution for subcutaneous or intraperitoneal injection.
- Manufacturing: Produced by Peptide Sciences USA with 99% purity, verified by HPLC and Mass Spectrometry.
- Usage Guidelines: Reconstitute with 2 mL bacteriostatic water (5 mg/mL) and administer 100–300 mcg subcutaneously or intraperitoneally, 1–2 times daily, in research protocols. Use under professional supervision. [](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776863/)
- Storage: Store lyophilized powder at -20°C for long-term stability or 4°C for short-term use (up to 3–4 weeks). After reconstitution, refrigerate at 2–8°C and use within 30 days.
- Safety: Preclinical studies report minimal side effects; limited human data requires research oversight. Caution advised in cancer studies due to potential pro-tumoral effects in TNBC models.
This peptide is for research purposes only, fueling discoveries in neuroprotection and anti-aging.
Legal Disclaimer
Humanin 10 mg is supplied for research purposes only and is not FDA-approved for human use. It is banned by the World Anti-Doping Agency (WADA) for performance-enhancing use. It is not intended to diagnose, treat, cure, or prevent any condition. Consult a licensed professional before use. Peptide Sciences USA assumes no liability for misuse. All information is educational and based on preclinical research.
Frequently Asked Questions
What is Humanin peptide used for?
Humanin fuels research into neuroprotection, mitochondrial health, and anti-aging, targeting Alzheimer's, diabetes, and cardiovascular health.
What is the role of Humanin as a potential preventative and therapeutic in Alzheimer's disease?
Humanin protects neurons from amyloid-beta and FAD gene toxicity, reducing Aβ plaques by up to 50% and improving cognition in AD mouse models.
What is the half-life of Humanin?
Preclinical studies show Humanin's half-life is ~1–2 hours in mice after intraperitoneal injection, extended with analogs like HNGF6A.
How to increase Humanin?
Research suggests exercise, caloric restriction, or Humanin analog (e.g., HNG) administration may boost endogenous levels in preclinical models.
How is Humanin 10 mg administered in research?
Mix the 10 mg vial with 2 mL bacteriostatic water and inject 100–300 mcg subcutaneously or intraperitoneally, 1–2 times daily, for research.
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