P21 5 mg
- Active Substance: P021 (CNTF mimetic)
- Concentration: 5 mg per vial
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: P021
- Molecular Formula: C30H54N6O5
- Molecular Weight: 578.8 g/mol
- Sequence: Ac-DGGL(A)G-NH2
- Synonyms: P021, Peptide 6c derivative, CNTF mimetic
P21 5 mg – Surge of Neural Renewal
Fuel Your Cognitive Research
Picture a lab where memory sharpens, neurons regenerate, and Alzheimer's pathology slows. P21 5 mg from Peptide Sciences USA makes this real. This nootropic peptide boosts BDNF, enhances synaptic plasticity, and fights tau and amyloid plaques, driving breakthroughs in cognitive health and neuroprotection. It's your surge for leading transformative research, crafted for trailblazing researchers like you.
The Science Behind Neural Renewal
P21 (P021, sequence: Ac-DGGL(A)G-NH2) is a synthetic mimetic of ciliary neurotrophic factor (CNTF), modified with an adamantane group for blood-brain barrier penetration. It increases BDNF and TrkB expression (150% increase in mitotic cells in the dentate gyrus), promoting neurogenesis and inhibiting tau and amyloid plaque formation. In mouse models, P21 improved memory (71% vs. 41% correct responses) and spatial reasoning.
It also reduces GSK3-beta activity, decreasing tau phosphorylation and amyloid-beta production, key Alzheimer's hallmarks. P21 enhances synapsin I, GluR1, and NR1 levels, supporting synaptic plasticity in both healthy and diseased brains. The 5 mg dosage is ideal for studying Alzheimer's, Parkinson's, traumatic brain injury, and cognitive enhancement, with potential in stress resilience and retinal health.
Why P21 5 mg Fuels Your Studies
P21 isn't just a peptide—it's a surge that transforms cognitive research. Here's what makes it shine:
- Cognitive Enhancement: Improves memory (71% correct responses) and spatial reasoning.
- Neuroprotection: Inhibits tau and amyloid plaques, slowing Alzheimer's pathology.
- Neurogenesis Boost: Increases BDNF and mitotic cells by 150% in the dentate gyrus.
- Synaptic Plasticity: Enhances synapsin I, GluR1, and NR1 for better neural connections.
- Top Quality: Crafted by Peptide Sciences USA with 99% purity for reliable results.
With P21 5 mg, you're not just studying—you're leading a breakthrough in neural renewal and cognitive vitality.
Product Specifications
Peptide Sciences USA's P21 5 mg is your key to cutting-edge cognitive studies. Here's the breakdown:
- Composition: Contains 5 mg P21 (C30H54N6O5, 578.8 g/mol).
- Pack Size: Single vial of lyophilized powder, requiring reconstitution for subcutaneous or intranasal administration.
- Manufacturing: Produced by Peptide Sciences USA with 99% purity, verified by HPLC and Mass Spectrometry.
- Usage Guidelines: Reconstitute with 1–2 mL bacteriostatic water (2.5–5 mg/mL). Inject 100–500 mcg subcutaneously or apply 500 mcg–1 mg intranasally daily for 4–6 weeks in research protocols. Use under professional supervision.
- Storage: Store lyophilized powder at -20°C for long-term stability or 4°C for short-term use (up to 3–4 weeks). After reconstitution, refrigerate at 2–8°C and use within 4–6 weeks.
- Safety: Preclinical studies report no significant side effects; rare mild tiredness may occur. Limited human data requires oversight.
This peptide is for research purposes only, driving discoveries in cognitive health and neuroprotection.
Legal Disclaimer
P21 5 mg is supplied for research purposes only and is not FDA-approved for therapeutic use, per regulations as of 2025. It is banned by the World Anti-Doping Agency (WADA) for performance-enhancing use. It is not intended to diagnose, treat, cure, or prevent any condition. Consult a licensed professional before use. Peptide Sciences USA assumes no liability for misuse. All information is educational and based on preclinical research.
Frequently Asked Questions
What does the P21 peptide do?
P21 boosts BDNF, promotes neurogenesis, enhances memory, and reduces tau and amyloid plaques in Alzheimer's models.
What is the role of the P21 protein?
The P21 protein (CDKN1A) regulates cell cycle progression, but P21 peptide (P021) mimics CNTF to promote neurogenesis and neuroprotection.
What peptides increase IQ?
P21 and Cerebrolysin may enhance cognitive function in animal models via BDNF and synaptic plasticity, but human IQ data is limited
What peptides increase dopamine levels?
P21 indirectly supports dopamine pathways via CNTF, which protects dopaminergic neurons in Parkinson's models. TAT-DATNT also increases dopamine.
How is P21 5 mg administered in research?
Mix the 5 mg vial with 1–2 mL bacteriostatic water. Inject 100–500 mcg subcutaneously or apply 500 mcg–1 mg intranasally daily for 4–6 weeks.
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