Semax 2 mg
- Active Substance: Semax Heptapeptide
- Concentration: 30 mg per vial
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Semax
- Molecular Formula: C37H51N9O10S
- Molecular Weight: 813.92 g/mol
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
- Synonyms: Semax, ACTH(4-10) Analog, Pro-Gly-Pro-ACTH
Semax is a synthetic heptapeptide derived from ACTH (adrenocorticotropic hormone) fragments, studied for its nootropic and neuroprotective properties. Delivered in a 2 mg injectable vial by Peptide Sciences USA, Semax has been widely researched for cognitive enhancement, recovery after ischemic events, stress resilience, and neuroinflammation regulation. Its broad activity profile makes it a staple in neurological and cognitive peptide research.
Mechanism of Action
Semax modulates neurotrophic factor expression, including Brain-Derived Neurotrophic Factor (BDNF), contributing to neuroplasticity, learning, and memory formation. It acts on melanocortin receptors (MC4 and MC5), which play a role in brain function, mood, and recovery from neural injury.
Additionally, Semax influences monoamine neurotransmitters — particularly dopamine and serotonin — by regulating their metabolism and reuptake. This results in enhanced mood, focus, and cognitive flexibility in research subjects. It has also demonstrated protective effects against oxidative stress and glutamate toxicity, both critical factors in neurodegenerative conditions.
In stroke models, Semax has been shown to reduce infarct size, preserve cognitive ability, and accelerate neural recovery. Its ability to upregulate antioxidant enzymes and modulate immune responses further supports its role in neuroprotection and post-injury rehabilitation research.
Unlike many nootropic agents, Semax exhibits high safety with low toxicity, no dependence risk, and excellent systemic tolerance when administered correctly in experimental settings.
Key Features & Benefits
- Cognitive Enhancement: Supports memory, attention, and learning through BDNF modulation and neurotransmitter balance.
- Neuroprotective Properties: Protects against oxidative stress and excitotoxicity in neural tissue models.
- Post-Stroke Recovery: Demonstrated in models to improve outcomes after ischemic brain injury and support faster cognitive rehabilitation.
- Improves Mood & Resilience: May help regulate dopamine and serotonin pathways involved in stress, anxiety, and depression.
- Safe & Well-Tolerated: Non-toxic with low risk of side effects in controlled lab use. No observed withdrawal or dependency risks.
- Injectable Format: 2 mg vial ensures accurate dosing for precision neurological research applications.
- USA Manufactured: Produced by Peptide Sciences under strict quality guidelines for research use only.
Legal Disclaimer
Disclaimer: This peptide is provided strictly for research and laboratory use. It is not intended for human consumption or therapeutic use. All users must be qualified professionals handling peptides in accordance with local laws and safety regulations. Misuse of this product may violate federal law.
Frequently Asked Questions
Semax is a synthetic neuropeptide studied for its cognitive-enhancing and neuroprotective effects, derived from ACTH fragments.
It is commonly researched for improving memory, focus, learning ability, and aiding recovery after stroke or brain injury.
Yes. It should be stored between 2–8°C and protected from direct light. Do not freeze.
Its effects in lab models typically last several hours per dose. The vial's shelf life is up to 24 months under proper storage.
Related Products
- Active Substance: Semax Heptapeptide
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- Molecular Formula: C37H51N9O10S
- Molecular Weight: 831.93 g/mol
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Synonyms: ACTH(4-10) analog, Heptapeptide Semax, Cognitive Peptide
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- Pack Size: Single vial (lyophilized powder)
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- Sequence: H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH
- Synonyms: Forkhead box protein O4 D-Retro-Inverso, FOXO4a, AFX, AFX1, MLLT7
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- Molecular Weight (HGH Fragment 176-191): 1817.12 g/mol
- Sequence (HGH Fragment 176-191): Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
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- Molecular Weight (Modified GRF): 3367.97 g/mol
- Sequence (Modified GRF): H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
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- Sequence (Ipamorelin): Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Synonyms: HGH Fragment 176-191 (AOD9604), Modified GRF (CJC-1295 No DAC), Ipamorelin (GHRP, Ghrelin mimetic)
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- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Peptide Blend
- Molecular Formula (HGH Fragment 176-191): C78H125N24O24S2
- Molecular Weight (HGH Fragment 176-191): 1817.12 g/mol
- Sequence (HGH Fragment 176-191): Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
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- Molecular Weight (CJC1295 No DAC): 3367.97 g/mol
- Sequence (CJC1295 No DAC): H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
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- Sequence (Ipamorelin): Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Synonyms: HGH Fragment 176-191 (AOD9604), CJC1295 No DAC (Mod GRF), Ipamorelin (GHRP, Ghrelin mimetic)