Sermorelin 10 mg
- Active Substance: Sermorelin (GHRH Analog)
- Concentration: 10 mg per vial
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Sermorelin
- Molecular Formula: C149H246N44O42S
- Molecular Weight: 3357.88 g/mol
- Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
- Synonyms: Sermorelin Acetate, GHRH (1-29)
Sermorelin is a synthetic analog of growth hormone–releasing hormone (GHRH), designed to stimulate the natural production of human growth hormone (GH) from the anterior pituitary. Supplied in a 10 mg injectable vial by Peptide Sciences USA, Sermorelin is widely researched for its roles in anti-aging, fat metabolism, muscle preservation, and overall recovery enhancement. It offers a physiological approach to growth hormone stimulation without direct hormonal replacement.
Mechanism of Action
Sermorelin mimics the endogenous GHRH(1-29) amino acid sequence, binding to specific GHRH receptors on somatotrophs in the pituitary gland. This binding triggers the synthesis and pulsatile release of endogenous growth hormone (GH), which in turn stimulates the liver to produce insulin-like growth factor 1 (IGF-1).
This cascade enhances cellular regeneration, protein synthesis, fat metabolism, and muscular repair in research models. Unlike exogenous GH administration, which can suppress the body's own production, Sermorelin promotes a regulated GH feedback loop, preserving hypothalamic-pituitary function.
Its long-term applications in research include the study of age-related hormone decline (somatopause), sarcopenia, and performance recovery. Sermorelin's shorter half-life compared to synthetic GH may allow for safer, more controlled research outcomes with minimal adverse effects when properly dosed.
In animal studies and early clinical models, Sermorelin has shown promising effects on body composition, sleep quality, skin elasticity, and immune function — all hallmarks of functional aging and endocrine optimization.
Key Features & Benefits
- Natural GH Stimulation: Stimulates the body's own production of growth hormone via GHRH receptor activation.
- Supports Muscle & Recovery: GH and IGF-1 boost protein synthesis, recovery speed, and lean muscle preservation in lab studies.
- Anti-Aging Research: Studied for its role in mitigating age-related hormonal decline, improving sleep, and skin integrity.
- Non-Suppressive: Unlike synthetic GH, Sermorelin enhances pituitary activity rather than replacing it.
- Metabolic Effects: May promote lipolysis, increased energy expenditure, and better glucose metabolism in test models.
- Manufactured in the USA: Made by Peptide Sciences under strict research-grade quality standards.
- Injectable Precision: 10 mg dose format enables exact research dosing for long-term endocrine studies.
Legal Disclaimer
Disclaimer: This compound is strictly intended for laboratory research. It is not approved by the FDA for medical or therapeutic use. All purchasers must handle this product in accordance with legal and safety standards for investigational peptides. Peptide Sciences USA assumes no liability for misuse or unauthorized application.
Frequently Asked Questions
It stimulates the pituitary gland to naturally release growth hormone, promoting IGF-1 production, tissue repair, and metabolic improvements.
Sermorelin is banned by some athletic organizations due to its GH-stimulating effects, which may offer performance-enhancing benefits in athletes.
The manufacturer voluntarily discontinued FDA approval; it was not due to safety concerns but rather commercial reasons. It is still available for research purposes.
Possible downsides in studies include injection site irritation, water retention, or transient fatigue. These effects are generally mild and reversible.
Related Products
- Active Substance: Sermorelin
- Concentration: 5 mg per vial
- Pack Size: 1 vial (lyophilized powder)
- Manufacturer: Dragon Pharma
- Brand Name: Sermorelin
- Molecular Formula: C149H246N44O42
- Molecular Weight: 3357.89 g/mol
- Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg
- Synonyms: GHRH(1-29), Growth Hormone Releasing Hormone fragment, Sermorelin Acetate
- Active Substance: Epitalon
- Concentration: 50 mg per vial
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Epitalon
- Molecular Formula: C14H22N4O9
- Molecular Weight: 390.35 g/mol
- Sequence: Ala-Glu-Asp-Gly
- Synonyms: Epithalon, AEDG, Epithalamin analog
- Active Substance: Proxofim (FOXO4-D-Retro-Inverso)
- Concentration: 10 mg per vial
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Proxofim
- Molecular Formula: C228H388N86O64
- Molecular Weight: 5358.05 g/mol
- Sequence: H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH
- Synonyms: Forkhead box protein O4 D-Retro-Inverso, FOXO4a, AFX, AFX1, MLLT7
- Active Substance: HGH Fragment 176-191 (6 mg), Modified GRF (CJC-1295 No DAC, 3 mg), Ipamorelin (3 mg)
- Concentration: 12 mg per vial (6 mg HGH Fragment 176-191 + 3 mg Modified GRF + 3 mg Ipamorelin)
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Peptide Blend
- Molecular Formula (HGH Fragment 176-191): C78H125N24O24S2
- Molecular Weight (HGH Fragment 176-191): 1817.12 g/mol
- Sequence (HGH Fragment 176-191): Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
- Molecular Formula (Modified GRF): C152H252N44O42
- Molecular Weight (Modified GRF): 3367.97 g/mol
- Sequence (Modified GRF): H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
- Molecular Formula (Ipamorelin): C38H49N9O5
- Molecular Weight (Ipamorelin): 711.85 g/mol
- Sequence (Ipamorelin): Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Synonyms: HGH Fragment 176-191 (AOD9604), Modified GRF (CJC-1295 No DAC), Ipamorelin (GHRP, Ghrelin mimetic)
- Active Substance: HGH Fragment 176-191 (6 mg), CJC1295 No DAC (3 mg), Ipamorelin (3 mg)
- Concentration: 12 mg per vial (6 mg HGH Fragment 176-191 + 3 mg CJC1295 + 3 mg Ipamorelin)
- Pack Size: Single vial (lyophilized powder)
- Manufacturer: Peptide Sciences USA
- Brand Name: Peptide Blend
- Molecular Formula (HGH Fragment 176-191): C78H125N24O24S2
- Molecular Weight (HGH Fragment 176-191): 1817.12 g/mol
- Sequence (HGH Fragment 176-191): Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
- Molecular Formula (CJC1295 No DAC): C152H252N44O42
- Molecular Weight (CJC1295 No DAC): 3367.97 g/mol
- Sequence (CJC1295 No DAC): H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
- Molecular Formula (Ipamorelin): C38H49N9O5
- Molecular Weight (Ipamorelin): 711.85 g/mol
- Sequence (Ipamorelin): Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Synonyms: HGH Fragment 176-191 (AOD9604), CJC1295 No DAC (Mod GRF), Ipamorelin (GHRP, Ghrelin mimetic)